Study programme | Français | ||
Molecular Biology | |||
Programme component of Bachelor's Degree in Biomedicine à la Faculty of Medicine and Pharmacy |
Code | Type | Head of UE | Department’s contact details | Teacher(s) |
---|---|---|---|---|
UM-B2-BIOMED-009-M | Compulsory UE | DECLEVES Anne-Emilie | M122 - Biologie moléculaire |
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Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Credits | Weighting | Term |
---|---|---|---|---|---|---|---|---|---|
| Français | 30 | 46 | 0 | 0 | 0 | 5.00 | 5.00 |
AA Code | Teaching Activity (AA) | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term | Weighting |
---|---|---|---|---|---|---|---|---|
M-BIMO-204 | Molecular biology | 30 | 30 | 0 | 0 | 0 | Q2 | |
M-PHPH-204 | From Genes to Physiopathology - an Integrated Approach | 0 | 16 | 0 | 0 | 0 | Q2 |
Unité d'enseignement | ||
---|---|---|
UM-B1-BIOMED-007-M Biochimie générale I | ||
UM-B2-BIOMED-001-M Biochimie générale II et méthodes d'expérimentations alternatives n'utilisant pas l'animal |
Objectives of Programme's Learning Outcomes
Learning Outcomes of UE
Students will complete their knowledge on the gene expression as well as on protein functions. Therefore, at the end of the lecture, the basic principles associated with the genetic material will be acquired. The lecture will discuss new concepts and advanced methodologies in the area of molecular biology, including the new generation sequencing. Theoretical concepts will help the students to extract information from public databases (internet) and understand published scientific results. During practical work in laboratory, they will perform several techniques such as cloning and manipulation of recombinant DNA (PCR, cloning, determination and computer analysis of sequences).
Content of UE
After a review of the structure of DNA, its modifications and gene expression ( replication , transcription, translation and compensation ), the course will cover the main techniques related to molecular biology , the genetic engineering ( electrophoresis of DNA , DNA cloning , restriction enzyme , ...) to transgenesis ; but also more modern techniques derived from the discovery of the human genome as microarray DNA , or pharmacogenomics techniques that lead us towards personalized medicine . The exercises and practical work will illustrate the theoretical lecture. The student will learn (1) how to understand and perform an experimental protocol, (2) how to analyse data and look for information on internet, (3) how to set up the best strategy to answer a scientific question. Moreover, including in the course entitled “Du gène à la physiopathologie: une approche intégrée », the students will have reminders of the specific biochemistry notions to realize the work. Demonstration of the use of different databases requisite to realize the work. Group exercise on a specific case from a gene acronym and a pathology.
Prior Experience
Not applicable
Type of Assessment for UE in Q1
Q1 UE Assessment Comments
Not applicable
Type of Assessment for UE in Q2
Q2 UE Assessment Comments
<u><strong>Lecture =</strong></u> open-ended questions and/or MCQ and/or right or false
<u><strong>Practical work =</strong></u> evaluated report, scored exercises + final test
<strong>Weighting =</strong> 10 % of total score
<u><strong>Section « Du gène à la physiopathologie : une approche intégrée » =</strong></u> presentation of a work (article)
<strong>Weighting =</strong> 10 % of total score
Type of Assessment for UE in Q3
Q3 UE Assessment Comments
The Q3 evaluation will be based on the lecture = MCQ and/or open-ended questions and/or right or false
Q1 UE Resit Assessment Comments (BAB1)
Not applicable
Type of Teaching Activity/Activities
AA | Type of Teaching Activity/Activities |
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M-BIMO-204 |
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M-PHPH-204 |
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Mode of delivery
AA | Mode of delivery |
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M-BIMO-204 |
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M-PHPH-204 |
|
Required Reading
AA | |
---|---|
M-BIMO-204 | |
M-PHPH-204 |
Required Learning Resources/Tools
AA | Required Learning Resources/Tools |
---|---|
M-BIMO-204 | The lecture will be illustrated by a slide show and Power Point animations . The slide of each course will be available to students via the Moodle platform . |
M-PHPH-204 | Not applicable |
Recommended Reading
AA | |
---|---|
M-BIMO-204 | |
M-PHPH-204 |
Recommended Learning Resources/Tools
AA | Recommended Learning Resources/Tools |
---|---|
M-BIMO-204 | reference book: J. Etienne 'Biochimie génétique - Biologie moléculaire' Masson |
M-PHPH-204 | Sans objet |
Other Recommended Reading
AA | Other Recommended Reading |
---|---|
M-BIMO-204 | None |
M-PHPH-204 | Explanation of the exercice, supplementary informations and courses of Biochemistry, Physiology (and Molecular Biology for the biomedical students) on the e-learning Platform Moodle |