Objectives of general skills

• Scientific skills
• Implement and independently carry out an experimental approach, validate a model by comparing its predications with experimental results, assess the limitations of the model's validity, and identify sources or error.
• In response to situations and aware of the methodological limitations: - Use common techniques of biochemistry, molecular biology, cell biology, studies of tissues and organs (i.e. link a macroscopic phenomenon to microscopic processes). - Use an experimental device in a biological model, know and use the concepts and techniques of animal physiology.
• Be familiar with biomedical science research tools, including bioinformatics tools.
• Appropriately select measuring instruments, analyse and process the signal obtained
• Be a responsible researcher: - Know how to base their reasoning on data obtained from scientific literature. - Know how to integrate an ethical dimension in their reasoning. - Be loyal (to the facts, to the team, and to intellectual property). - Do not tamper with results. - Do not exploit the work of others. - Demonstrate experimental rigor.
• Professional integration skills
• Be aware of ethical issues and apply ethical codes specific to life sciences in their behaviour
• Work independently: - Get organised, manage time and priorities, assess themself. - Master assessment methods. - Continue learning individually, prepare to educate themselves throughout life. - Demonstrate abstract thinking. - Be introduced to project management. - Show initiative.
• Demonstrate their ability to research, analyse and synthesise: - Research, analyse, use different sources of information and materials related to biomedical sciences, format them to draw up a summarised document, produced and broadcast them on digital media. - Carry out a study, identify and raise an issue in a predefined context, build and develop an argument, interpret the data and results, develop an overview, and propose extensions. - Question themselves, think critically, debate, and defend their ideas.
• Master written and oral scientific expression. Be independent in writing and show that they can communicate their thoughts, reason and organise their knowledge

UE's Learning outcomes

The students will be familiarized with the modern methodology used to discover active pharmacological compounds, with a focus on the phage display technology which is a fundamental scientific tool of the Molecular Imaging Laboratory (Department of General, Organic and Biomedical Chemistry) of the University of Mons. The applications in the field of therapeutics and particularly in that of medical molecular imaging will be developed.

UE Content

The course will be scheduled according to the following major plan:
- definition of biomarkers and presentation of the identification methodology;
- definition of the targeted molecular ligand;
- presentation of the high throughput screening methodology used in the discovery of the active pharmaceutical compounds;
- presentation of the methodology used to validate the active pharmaceutical compounds.
- the exigencies and advantages of the in vivo molecular imaging;
- molecular imaging of the cardiovascular system;
- molecular imaging of the nervous system;
- imaging of the liver function;
- molecular imaging of the renal function;
- cancer imaging

Prior experience

Sans objet

Term 1 for Integrated Assessment - type

• Oral examination
• Written examination

Term 2 for Integrated Assessment - type

• Written examination

Term 3 for Integrated Assessment - type

• N/A

Resit Assessment for IT - Term 1 (B1BA1) - type

• N/A