Objectives of general skills

• 1. Pharmaceutical expertise: Use a foundation of concepts and knowledge in health sciences and pharmaceutical sciences.
• Understand the chronology of a phenomenon and master the time scales and their representations
• 2. Scientific method: Solve pharmaceutical problems using their knowledge and critical mind.
• Understand and apply the basic principles of reasoning (obtaining data, analysis, synthesis, comparison, the rule of three, syllogism, analogy, Boolean logic, etc.)
• Use a hypothesis in inductive, deductive or abductive reasoning
• 3. Communication: Communicate in an appropriate, efficient, rigorous and respectful way in a professional perspective.
• Understand the basic rules of French (grammar, punctuation, connectors, etc.)
• Use a rich vocabulary linking concepts and words accurately
• Summarise, explain, and argue
• Work in a team
• 5. Quality: Assess themself, expand their knowledge and adapt their attitude.
• Manage time

UE's Learning outcomes

Students will complete their knowledge on the gene expression as well as on protein functions. The course will discuss new concepts and advanced methodologies in the area of molecular biology, including the human genome sequencing. Theoretical concepts will help the students to extract information from public databases (internet) and understand published scientific results. During practical work in laboratory, they will perform several techniques such as cloning and manipulation of recombinant DNA (PCR, cloning, determination and computer analysis of sequences).

UE Content

  The lecture will concern : 1. Background: flow of genetic information and expression of the genes. 2. General techniques of molecular biology (DNA banks, screening, PCR...) 3. The determination of the human genome sequencing, new discoveries and derivative tools (polymorphic DNA, pharmacogenomics, microarray and gene expression study). 4. Functional genomics: how to highlight the role of proteins encoded by newly identified genes. Practical works based on diverse molecular techniques (PCR, electrophoresis). The student will learn (1) how to understand and perform an experimental protocol, (2) how to analyse data and look for information on internet, (3) how to set up the best strategy to answer a scientific question. Moreover, including in the course entitled “Du gène à la physiopathologie: une approche intégrée », the students will have reminders of the specific biochemistry notions to realize the work. Demonstration of the use of different databases requisite to realize the work. Group exercise on a specific case from a gene acronym and a pathology.

Prior experience

Not applicable

Term 1 for Integrated Assessment - type

• N/A

Term 1 for Integrated Assessment - comments

Not applicable

Term 2 for Integrated Assessment - type

• Written examination
• Practical test
• Quoted exercices

Term 2 for Integrated Assessment - comments

Lecture = open-ended questions and MCQ with negative points
Practical work = evaluated report, scored exercises 
Section « Du gène à la physiopathologie : une approche intégrée » = Presentation of a work (article)

Term 3 for Integrated Assessment - type

• Written examination

Term 3 for Integrated Assessment - comments

Not applicable

Resit Assessment for IT - Term 1 (B1BA1) - type

• N/A

Resit Assessment for IT - Term 1 (B1BA1) - Comments

Not applicable