Objectives of Programme's Learning Outcomes

• In the field of chemistry, possess highly specialised and integrated knowledge and a wide range of skills adding to those covered in the Bachelor's programme in chemistry.
• Help lead and complete a major development project, individually or in teams, related to chemistry.
• Mobilise, articulate and promote the knowledge and skills acquired.
• Manage research, development and innovation within chemistry and/or its applications.
• Understand unprecedented problems in chemistry.
• Communicate clearly in the scientific domain.
• Communicate, both orally and in writing, their findings, original proposals, knowledge and underlying principles, in a clear, structured and justified manner.
• Develop and integrate a high degree of autonomy.
• Pursue their education and gain additional knowledge and new skills.
• Adapt and evolve in a new context.
• Apply high quality scientific methodology.
• Critically reflect on the impact of chemistry in general and projects to which they particularly contribute.
• Have acquired professional skills in relation to the objective defining the degree.
• Specialise in at least one sub-domain of chemistry.
• Help lead and complete a major development project, individually or in teams, related to chemistry.
• Mobilise, articulate and promote the knowledge and skills acquired.
• Manage research, development and innovation within chemistry and/or its applications.
• Understand unprecedented problems in chemistry.

Learning Outcomes of UE

The main objective of this course is to describe the major tools used to predict the potential toxic effects of chemicals.  Consequently, at the end of this class, the students will be able to :

-  understand and describe the predictive approach based on structure-activity relationship (QSAR)

- Use the available softwares for the prediction of the metabolism and the safety of a substance from its chemical structure

- identify the most appropriate in vitro and in vivo assays for risk assessment based on the target organ

- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology

- design a study protocol for preclinical toxicology evaluation

Content of UE

The class will be divided in two sections:

1. in silico Models (QSAR, CADD, and expert systems)

2. in vitro et in vivo Models (mutagenicity, developmental toxicity, major target organs, and the genomics, proteomics, and metabonomics approaches applied to toxcicology)

Prior Experience

Not applicable

Type of Assessment for UE in Q2

• Written examination

Method of calculating the overall mark for the Q2 UE assessment

For each AA (Leraning activity), the exam is composed of two parts (global quote on 20 points) :
1) a series of 20 MCQs (quote on 10 points)
2) an open quesiton (quote on 10 points)

The global quote for the UE is the mean of the quotes obtained in each AA.

Q2 UE Assessment Comments

For each AA (Leraning activity), the exam is composed of two parts (global quote on 20 points) :
1) a series of 20 MCQs (quote on 10 points)
2) an open quesiton (quote on 10 points)

The global quote for the UE is the mean of the quotes obtained in each AA.

Type of Assessment for UE in Q3

• Written examination

Method of calculating the overall mark for the Q3 UE assessment

same as Q2

Q3 UE Assessment Comments

same as Q2