Objectives of Programme's Learning Outcomes

• Understand, describe, analyse and prioritise biological phenomena
• Understand basic scientific knowledge and be able to use it
• Problem-solve
• Understand the expression of biological realities in absolute or relative terms, the orders of magnitude, proportions and probability
• Abstract, understand and apply mathematical translations of the main laws and biological phenomena
• Understand and use different graphical representations of numerical values and their relationships
• Perceive spatial distribution, and understand two- and three-dimensional representations and interconvert them
• Understand the chronology of a phenomenon and master the time scales and their representations
• Manipulate concepts of concentration and prepare solutions
• Control the molecular, morphological and functional approaches of normal and pathological conditions
• Understand experimental protocols in the biomedical domain
• Integrate concepts from different approaches/disciplines in a complex biomedical problem
• Explain how molecular, morphological and functional modifications constitute pathological states and vice versa
• Develop reasoning skills
• Understand and apply the basic principles of reasoning (obtaining data, analysis, synthesis, comparison, the rule of three, syllogism, analogy, Boolean logic, etc.)
• Work with efficiency / accuracy / precision
• Develop critical thinking, test and monitor conclusions understanding the domain of validity, and explore alternative hypotheses
• Manage doubt and uncertainty
• Demonstrate developed interpersonal skills
• Use a rich vocabulary linking concepts and words accurately
• Adapt lexical and syntactic choices in communication register (everyday language, medical language or scientific terminology)
• Summarise, explain, and argue
• Work in a team
• Share knowledge and information
• Submit reviews, reports and give oral presentations
• Manage resources
• Manage time
• Prioritise
• Use basic IT and bibliographic resources.
• Manage their studies
• Self-assess and give feedback
• Be open to research and demonstrate scientific curiosity

Learning Outcomes of UE

Biochemistry is at the frontier of biological science and chemical science. Indeed, biochemistry seeks to understand the chemical basis for all life processes. It is therefore a key discipline in medical, biomedical and pharmaceutical research. Indeed, biochemistry helps to understand biological processes, allows to identify the mechanisms involved in disease and especially allows to better define a treatment. The purpose of this course will be to acquire the basic knowledge of biochemical functions (molecule structure, enzymology, bioenergetic). Knowledges that will then be used to understand and interpret biochemical processes. <b>At the end of this course, students will be able to</b>: ·       understand the role of the 4 main classes of small organic molecules of the cells (aa, monosaccharides, nucleotides and lipids) in the main biochemical pathways; ·       understand the acid-base chemistry and the importance of water in the biochemical processes; ·       interpret the impact of changes in pH on ionizable groups of a peptide or a protein; ·       understand the concept that the structure of a given biomolecule is directly related to its function; ·       understand the role and the regulation of enzymes in biochemical reactions; ·       understand the energetics of life and associate the notion of bio-energy to the metabolic pathways; ·       integrate the metabolism of glucose in anaerobic or aerobic conditions; ·       understand the regulation of glucose metabolism; ·       address without difficulties the course of biochemistry in BA2.

Content of UE

<b>The lecture will be set up in three main parts:</b> I. Reminder of the 4 main classes of small organic molecules of the cells, the water structure, pH and the acid-base chemistry II. Structures and functions of the proteins and enzymes III. The energetics of life, and carbohydrate metabolism and regulation ==> The<b> lecture </b>(face-to-face) will be associated with <b>practical works</b> (supervised work, exercices and e-learning)  

Prior Experience

Sans objet

Type of Assessment for UE in Q2

• Written examination
• Practical test
• Quoted exercices
• eTest

Q2 UE Assessment Comments

<b>Lecture</b> = MCQ with negative points, and/or true or false, and/or open-ended questions <b>eTes</b>t = final test - <b>Weighting </b>on Q2 = 10%
<b>Practical work </b>= evaluated report, scored exercices + final test - <b>Weighting on Q2</b> = 10%  

Type of Assessment for UE in Q3

• Written examination

Q3 UE Assessment Comments

The Q3 evaluation will be based on the lecture = MCQ with negative points, and/or ture or false, and/or open-ended questions. The score reached in Q2 regarding eTest and practical work will be added in Q3 fo a w<b>eighting </b>of 20%.