Objectives of Programme's Learning Outcomes

• Imagine, design, implement and operate compounds/products to specific properties and chemical and biochemical processes leading to obtaining these by integrating the needs, contexts and issues (technical, economic, societal, ethical, safety and environmental).
• Identify complex problems to be solved and formulate the specifications by integrating client needs, contexts and issues (technical, economic, societal, ethical, safety and environmental).
• On the basis of modelling, design one or more projects and solutions addressing the problem raised; evaluate them in light of various parameters of the specifications.
• Evaluate the approach and results for their operation and adaptation (optimisation, quality, environment, security, etc.).
• Mobilise a structured set of scientific knowledge and skills and specialised techniques in order to carry out missions of chemical engineering and materials science, with a focus on chemical industry processes, using their expertise and adaptability.
• Master and appropriately mobilise knowledge, models, methods and techniques relating to material properties, chemical changes, transport phenomena and thermodynamic properties, characterisation techniques and methods of chemical and material compounds, environmentally friendly production processes, and their optimisation and simulation.
• Analyse and model a process or way of producing a compound by critically selecting theories and methodological approaches (modelling, calculations), and taking into account multidisciplinary aspects.
• Identify and discuss possible applications of new and emerging technologies in the chemical, petrochemical, biotechnology, pharmaceutical and polymer industries.
• Assess the relevance of models and results given the current state of science and characteristics of the problem.
• Communicate and exchange information in a structured way - orally, graphically and in writing, in French and in one or more other languages - scientifically, culturally, technically and interpersonally, by adapting to the intended purpose and the relevant public.
• Argue to and persuade clients, colleagues, teachers and boards, both orally and in writing.
• Select and use the written and oral communication methods and materials adapted to the intended purpose and the relevant public.
• Use and produce scientific and technical documents (reports, plans, specifications, etc.) adapted to the intended purpose and the relevant public.
• Contribute by researching the innovative solution of a problem in engineering sciences.
• Acquire and analyse data rigorously.
• Adequately interpret the results taking into account the reference framework within which the research was developed.
• Adopt a professional and responsible approach, showing an open and critical mind in an independent professional development process.
• Show an open and critical mind by bringing to light technical and non-technical issues of analysed problems and proposed solutions.
• Exploit the different means available in order to inform and train independently.

Learning Outcomes of UE

The course on industrial biotechnology introduction enables students to acquire the following knowledge:
- know the biochemical coumponds and their functions;
- know the main components of a cell and their functions (microbial physiology) ;
- understand cellular function (metabolism, replication, enzymology);
- Represent enzymatic and microbial reactions through appropriate kinetic laws;
- Understand and use the basics of engineering bioprocesses and biorefineries ;
- Understand the complexity of extrapolating a process from a laboratory to a driver and then to an industry;
- Understand online monitoring and regulation problems
- Choose a method of separation / purification based on the constraints

UE Content: description and pedagogical relevance

This course is divided into parts.
The first part is dedicated to the fundamentals of biochemistry, microbiology, metabolism and enzymology.
A general introduction concerning the exploitation of biomass as a renewable resource and the progressive conversion of refineries into biorefineries is proposed.
Some legal and normative concepts are taught (contained use, security level laboratories).
The biocatalysis and bioreactor aspects are then discussed by the characterisation of the mechanisms (enzymatic and microbial biocatalysis), and engineering microbial bioreactors (flows, continuous reactors, batch, fed-batch, airlift, the balance sheets of materials, heat exchanges).
Associated with these descriptions, scale up problems and monitoring of processes are presented. Some examples of models are detailed.
The purification aspects (membranes, chromatography, precipitation, etc.) are then discussed in the light of the final use of bioproduct.
Some examples of major industrial bioprocesses are described (antibodies, vaccines, bioethanol, biogas, treatment of urban waters).

Prior Experience

Organic chemistry basic concepts (structure, function, spatial representations) and basic laboratory techniques (analytical and organic chemistry) are required to follow this course unit.