Objectives of Programme's Learning Outcomes

Learning Outcomes of UE

The main objective of this course is to provide to the students the major tools used to predict the potential toxic effects of chemicals.  Consequently, at the end of this course, the students will be able to :

-  understand and describe the predictive approach based on structure-activity relationship (QSAR)

- Use the available predictive softwares for the prediction of the metabolism and the safety of a substance from its chemical structure

- identify the most appropriate in vitro and in vivo assays for risk assessment based on the target organ

- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology

- design a study protocol for preclinical toxicology evaluation 
 

Content of UE

The class will be divided in two sections:

1. in silico Models (QSAR, CADD, and expert systems)

2. in vitro et in vivo models (mutagenicity, developmental toxicity, major target organs, and genomics, proteomics, and metabonomics approaches applied to toxcicology)

Prior Experience

Fundamentals in biology and chemistry
Genral toxicology class

Type of Assessment for UE in Q2

• Written examination

Method of calculating the overall mark for the Q2 UE assessment

For each AA (learning activity), the exam is composed of two parts (global quote on 20 points) :
1) a series of 20 MCQs (quote on 10 points)
2) an open quesiton (quote on 10 points)

For those students enrolled in both AAs, the global quote for the full UE (teaching unit) is the mean of both quotes obtnained for each AA.

Q2 UE Assessment Comments

For each AA, the exam is composed of two parts (global quote on 20 points) :
1) a series of 20 MCQs (quote on 10 points)
2) an open quesiton (quote on 10 points)

Type of Assessment for UE in Q3

• Written examination

Method of calculating the overall mark for the Q3 UE assessment

same as Q2

Q3 UE Assessment Comments

same as Q2