 | Study programme 2021-2022 | Français | |
 | Agents toxiques spécifiques - Agents biologiques | ||
Programme component of Graduate Certificate in Hazardous Substances Advisor à la Faculty of Engineering |
| Code | Type | Head of UE | Department’s contact details | Teacher(s) |
|---|---|---|---|---|
| UI-U1-CONSUB-203-M | Compulsory UE | COLET Jean-Marie | M125 - Biologie humaine et Toxicologie |
|
| Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Credits | Weighting | Term |
|---|---|---|---|---|---|---|---|---|---|
| Français | 30 | 0 | 0 | 0 | 0 | 4 | 4.00 | Full academic year |
| AA Code | Teaching Activity (AA) | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term | Weighting |
|---|---|---|---|---|---|---|---|---|
| I-CERT-203 | Agents toxiques spécifiques - Agents biologiques | 30 | 0 | 0 | 0 | 0 | A |
| Programme component |
|---|
Learning Outcomes of UE
At the end of this course, students will be able to:
- Explain concepts in ADME (Absorption / Distribution / Métaboslime / Disposal)
- Describe the fundamentals underlying the toxic effects of chemicals
- Understand the most common models and methods applied in the risk assessment of chemicals
Content of UE
1. Concepts in ADME (Administration, Distribution, Metabolism, Elimination)
2. Biotransformation and bioactivation of chemicals
3. Modulators of toxic effetcs
4. Conventional procedures of risk assessment
5. Major toxic mechanisms (oxidative stress, disruption of calcium homeostasis, necrosis and apoptosis, cell proliferaiton, covanlent binding to macromolecules, immunotoxicity, enzymes inactivation, interaction with ionic transporters)
Prior Experience
Fundamentals in organic chemistry
Type of Assessment for UE in Q1
- Written examination
Q1 UE Assessment Comments
Multiple choice Q&A test
Type of Assessment for UE in Q2
- Written examination
Q2 UE Assessment Comments
Multiple choice Q&A test
Type of Assessment for UE in Q3
- Written examination
Q3 UE Assessment Comments
Multiple choice Q&A test
Type of Resit Assessment for UE in Q1 (BAB1)
- N/A
Q1 UE Resit Assessment Comments (BAB1)
Not applicable
Type of Teaching Activity/Activities
| AA | Type of Teaching Activity/Activities |
|---|---|
| I-CERT-203 |
|
Mode of delivery
| AA | Mode of delivery |
|---|---|
| I-CERT-203 |
|
Required Reading
| AA | |
|---|---|
| I-CERT-203 |
Required Learning Resources/Tools
| AA | Required Learning Resources/Tools |
|---|---|
| I-CERT-203 | 1. Concepts in ADME (Administration, Distribution, Metabolism, Elimination) 2. Biotransformation and bioactivation of chemicals 3. Modulators of toxic effetcs 4. Conventional procedures in risk assessment 5. Major toxic mechanisms (oxidative stress, disruption of calcium homeostasis, necrosis and apoptosis, cell proliferaiton, covalent binding to macromolecules, immunotoxicity, enzymes inactivation, interaction with ionic transporters) 6. Determination of a Reference dose (INERIS methodology) |
Recommended Reading
| AA | |
|---|---|
| I-CERT-203 |
Recommended Learning Resources/Tools
| AA | Recommended Learning Resources/Tools |
|---|---|
| I-CERT-203 | Not applicable |
Other Recommended Reading
| AA | Other Recommended Reading |
|---|---|
| I-CERT-203 | Not applicable |