Study programme 2019-2020Français
Predictive Toxicology (including Metabolomics)
Programme component of Master's in Biochemistry and Molecular and Cell Biology à la Faculty of Science

Students are asked to consult the ECTS course descriptions for each learning activity (AA) to know what assessment methods are planned for the end of Q3

CodeTypeHead of UE Department’s
contact details
Teacher(s)
US-M1-SCBBMC-016-MOptional UECOLET Jean-MarieM125 - Biologie humaine et Toxicologie
  • COLET Jean-Marie

Language
of instruction
Language
of assessment
HT(*) HTPE(*) HTPS(*) HR(*) HD(*) CreditsWeighting Term
  • Français
Français30000044.002nd term

AA CodeTeaching Activity (AA) HT(*) HTPE(*) HTPS(*) HR(*) HD(*) Term Weighting
M-BHTO-302Predictive toxicology - part 1150000Q2
M-BHTO-303Predictive toxicology - part 2150000Q2
Programme component

Objectives of Programme's Learning Outcomes

  • In the field of biological sciences and particularly in the field of the biochemistry, molecular and cell biology, possess highly specialised and integrated knowledge and a wide range of skills adding to those covered in the Bachelor's programme in biological sciences.
  • Manage and lead research, development and innovation projects.
    • Understand unprecedented problems in biological sciences, and more specifically in biochemistry and molecular and cell biology and its applications.
    • Methodically research valid scientific information, critically analyse, propose and argue potentially innovative solutions to targeted problems.
  • Master communication techniques.
    • Communicate, both orally and in writing, their findings, original proposals, knowledge and underlying principles, in a clear, structured and justified manner.
  • Develop and integrate a high degree of autonomy.
    • Aquire new knowledge independently.
    • Pursue further training and develop new skills independently.

Learning Outcomes of UE

The main objective of this course is to provide to the students the major tools uise di the rediciton of potektail toxic effects of chemicals.  Consequently, at the end of this course, the students will be able to :

-  understand and describe the predictive approach based on structure-activity relationship (QSAR)

- Use predictive softwares (Meteor and Derek) for the prediction of the metabolism and the safety of a substance from its chemical structure

- identify the most appropriate in vitro and in vivo assays for risk assessment based on the target organ

- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology

- design a study protocol for preclinical toxicology evaluation 
Not applicable

Content of UE

After a short introduction on the basic concepts in toxicology, the course will be divided into two sections:

1. in silico Models /QSAR

2. in vitro et in vivo Models (mutagenicity, developmental toxicity, major target organs)

3. Genomics, proteomics, and metabonomics approaches applied to toxcicology

Prior Experience

Not applicable

Type of Assessment for UE in Q2

  • Oral Examination

Q2 UE Assessment Comments

Not applicable

Type of Assessment for UE in Q3

  • Oral examination

Q3 UE Assessment Comments

Not applicable

Type of Teaching Activity/Activities

AAType of Teaching Activity/Activities
M-BHTO-302
  • Cours magistraux
  • Conférences
M-BHTO-303
  • Cours magistraux
  • Conférences

Mode of delivery

AAMode of delivery
M-BHTO-302
  • Face to face
M-BHTO-303
  • Face to face

Required Reading

AA
M-BHTO-302
M-BHTO-303

Required Learning Resources/Tools

AARequired Learning Resources/Tools
M-BHTO-302Not applicable
M-BHTO-303Not applicable

Recommended Reading

AA
M-BHTO-302
M-BHTO-303

Recommended Learning Resources/Tools

AARecommended Learning Resources/Tools
M-BHTO-302Not applicable
M-BHTO-303Not applicable

Other Recommended Reading

AAOther Recommended Reading
M-BHTO-302Not applicable
M-BHTO-303Not applicable
(*) HT : Hours of theory - HTPE : Hours of in-class exercices - HTPS : hours of practical work - HD : HMiscellaneous time - HR : Hours of remedial classes. - Per. (Period), Y=Year, Q1=1st term et Q2=2nd term
Date de génération : 13/07/2020
20, place du Parc, B7000 Mons - Belgique
Tél: +32 (0)65 373111
Courriel: info.mons@umons.ac.be