 | Study programme 2019-2020 | Français | |
| Neurotoxicology and Safety Pharmacology | |||
Learning Activity |
| Code | Lecturer(s) | Associate Lecturer(s) | Subsitute Lecturer(s) et other(s) | Establishment |
|---|---|---|---|---|
| M-DOYM-129 |
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| Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term |
|---|---|---|---|---|---|---|---|
| Anglais | Anglais | 30 | 0 | 0 | 0 | 0 | Q1 |
| Description of the modifications to the Q3 2019-2020 online assessment procedures (Covid-19) |
|---|
| No exam at Q3. All students already validated this course during the year |
Content of Learning Activity
Reminder in Neurophysiology/Neuropharmacology: Structures, Functions of Nervous System (NS), neurotransmitters, barriers, metabolism, development. Pharmacology, Safety pharmacology, Toxicology notions: class effects, on-target & off target effects, dose, concentration, brain penetration, routes of administration...
Safety Pharmacology: Regulatory requirement for Nervous System, Acute & functional effects, Neurobehavioural assessment, Seizure liability, Drug abuse potential, Testing
Neurotoxicology (mature organisms): Regulatory requirement (drug, chemicals), Toxic Syndromes, Heavy metals, Gaz, Chemical compounds, Pesticids, Alcohol, Neurotoxins: animal, plants, mushrooms, bacteria.. Testing
Developmental Neurotoxicology: NS Development, critical periods, Regulatory requirement, Heavy metals, chemical compounds, pesticids, alcohol, tobacco, Testing
Endocrine disruptors: effects during NS development, effects on sex specific brain regions
Risk assessment: Hazard identification, on/off target effect, intrinsic toxicity, DMPK, exposure, risk evaluation and mitigation, population, acute and long-term effects
Required Learning Resources/Tools
Not applicable
Recommended Learning Resources/Tools
Not applicable
Other Recommended Reading
Toxicologie clinique, de Baud & Garnier (2017) Lavoisier Médecine Ed.
Handbook of developmental Neurotoxicology, Slikker et al. (2018) Academic Press Ed.
Mode of delivery
- Face to face
Type of Teaching Activity/Activities
- Cours magistraux
Evaluations
The assessment methods of the Learning Activity (AA) are specified in the course description of the corresponding Educational Component (UE)