Study programme 2019-2020 | Français | ||
Research Techniques in Neuroscience | |||
Learning Activity |
Code | Lecturer(s) | Associate Lecturer(s) | Subsitute Lecturer(s) et other(s) | Establishment |
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M-DOYM-122 |
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Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term |
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Anglais | Anglais | 45 | 0 | 0 | 0 | 0 | Q1 |
Organisational online arrangements for the end of Q3 2019-2020 assessments (Covid-19) |
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Description of the modifications to the Q3 2019-2020 online assessment procedures (Covid-19) |
The "Research Techniques in Neuroscience" exam consists in a presentation and analysis of a research article from Neurosciences field published in peer-review journal. This presentation will be done orally, in English, by Microsoft teams meeting. The student will receive by email several articles proposed by the teacher. The student will have one week to choose the article he/she will present at the exam and to communicate his/her choice to Aurore Colomar. The student will have at least 2 weeks more to read the article and prepare the presentation. On the exam, he/she will have to present during 20 min max the article and to answer to questions during 10 minutes. The planning of the exam will be communicated later. Good luck and good work! Aurore Colomar |
Content of Learning Activity
Research techniques applied to Neurosciences. Experimental models: animal models, in vitro, in silico. Rodents, primates, other mammalians, C.elegans, drosophila, zebrafish. Primary cell cultures, cell lines, stem-cell derived cells (Neurons & glial cells), organotypic cultures, slices, organoïds. Electrophysiology: Extracellular, intracellular recordings, patch-clamp and its configurations, automated patch-clamp. Models used in electrophysiology: neurons, glia, cell culture, slices, in vivo. Optogenetics. Behavior: elevated plus maze, preference place, forced swimming test, social interactions. Microscopy: confocal, multi-photon, electronic. Fluorescence, FRET, calcium imaging. Fixed and non-fixed tissue, reconstitution of tissue. Retrograde viral tracing. Molecular biology: In situ hybridization, single-cell RT-PCR, transgenesis (CrispR, Cre/Lox), inducible system, siRNA
Gene and cellular therapies : Parkinson's disease, sleep disorder, neuronal cell death
Functional imaging : MRI, PET-scan
Electroencephalography, magneto-encephalography, EROS: event-related optical signal
Required Learning Resources/Tools
Not applicable
Recommended Learning Resources/Tools
Not applicable
Other Recommended Reading
Not applicable
Mode of delivery
Type of Teaching Activity/Activities
Evaluations
The assessment methods of the Learning Activity (AA) are specified in the course description of the corresponding Educational Component (UE)