Objectives of Programme's Learning Outcomes

Learning Outcomes of UE

The main objective of this course is to provide to the students the major tools uise di the rediciton of potektail toxic effects of chemicals.  Consequently, at the end of this course, the students will be able to :

-  understand and describe the predictive approach based on structure-activity relationship (QSAR)

- Use predictive softwares (Meteor and Derek) for the prediction of the metabolism and the safety of a substance from its chemical structure

- identify the most appropriate in vitro and in vivo assays for risk assessment based on the target organ

- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology

- design a study protocol for preclinical toxicology evaluation 
 

Content of UE

After a short introduction on the basic concepts in toxicology, the course will be divided into two sections:

1. in silico Models /QSAR

2. in vitro et in vivo Models (mutagenicity, developmental toxicity, major target organs)

3. Genomics, proteomics, and metabonomics approaches applied to toxcicology

Prior Experience

Fundamentals in biology and chemistry

Type of Assessment for UE in Q2

• Written examination
• eTest

Q2 UE Assessment Comments

Not applicable

Type of Assessment for UE in Q3

• Written examination
• eTest

Q3 UE Assessment Comments

Not applicable