Objectives of Programme's Learning Outcomes

• Professional integration skills
• Master written and oral scientific expression. Be independent in writing and show that they can communicate their thoughts, reason and organise their knowledge
• Make a presentation illustrating arguments adapted to the object, the circumstances and the public: speak in public

Learning Outcomes of UE

The learning activity or teaching objective results in
- familiarizing the student with several major topic of biological and medical sciences currently exploited by the pharmaceutical industry,
- accounting for some "universality" of molecular pathogenic mechanisms  contributig to the development of major human diseases,
- reviewing pharmacological therapies addressing these molecular mechanisms,
- providing the student with the bases for writing a dissertation on a pharmacological approach at the cross-road of a chosen theme (pathophysiological mechanisms used as therapeutic target, for instance either oxidative stress, or inflammatory stress, or apoptosis, etc.) and a chosen pathology (for instance, cancer or diabetes or cerebral anoxic infarct, etc.). This dissertation is asked to comply with instructions given by the teacher in order to obtain a minireview article-like dissertation. The student is appreciated on both the the dissertation and its oral presentation. These written and oral presentations are usuallly performed by groups of 3 students by dissertation.
 

Content of UE

The course essentially develops the following themes (with the associated therapeutic approaches) : oxidative stress, inflammatory stress with the inflammasome, hormonal nuclear receptor members (essentially PPARs, Peroxisome Proliferator-Activated Receptors), lipoprotein metabolism, unsatruatred fatty acid families and derived mediators (including prostaglandins, thromboxanes, leucotrienes, lipoxins, resolvins, neuroprotectins) and oxidized lipids, autophagy, apoptosis and targeted therapies in cancer. A recall of previous lessons is done at the beginning of each course in order to keep in mind the global way of the academic formation given to students.

Prior Experience

Not applicable

Type of Assessment for UE in Q1

• Presentation and/or works

Q1 UE Assessment Comments

Written and oral presentation of a dissertation or even a written presentation only, depending on public health constraints. The student (or the group of 2 to 3 students) presents and relativizes an existing therapeutic approach (or one proposed by the student(s)) which must associate one of the themes of the course (drugs for either oxidative stress or inflammatory stress, or autophagy for example) within the framework of the treatment of a disease or a group of diseases (Alzheimer's disease, cardiovascular disease, cancer for example). 

Type of Assessment for UE in Q2

• Presentation and/or works

Q2 UE Assessment Comments

Written and oral presentation of a dissertation or even a written presentation only, depending on public health constraints. The student (or the group of 2 to 3 students) presents and relativizes an existing therapeutic approach (or one proposed by the student(s)) which must associate one of the themes of the course (drugs for either oxidative stress or inflammatory stress, or autophagy for example) within the framework of the treatment of a disease or a group of diseases (Alzheimer's disease, cardiovascular disease, cancer for example). 

Type of Assessment for UE in Q3

• Presentation and/or works

Q3 UE Assessment Comments

Written and oral presentation of a dissertation or even a written presentation only, depending on public health constraints. The student (or the group of 2 to 3 students) presents and relativizes an existing therapeutic approach (or one proposed by the student(s)) which must associate one of the themes of the course (drugs for either oxidative stress or inflammatory stress, or autophagy for example) within the framework of the treatment of a disease or a group of diseases (Alzheimer's disease, cardiovascular disease, cancer for example). 

Type of Resit Assessment for UE in Q1 (BAB1)

• Presentation and/or works

Q1 UE Resit Assessment Comments (BAB1)

Written and oral presentation of a dissertation or even a written presentation only, depending on public health constraints. The student (or the group of 2 to 3 students) presents and relativizes an existing therapeutic approach (or one proposed by the student(s)) which must associate one of the themes of the course (drugs for either oxidative stress or inflammatory stress, or autophagy for example) within the framework of the treatment of a disease or a group of diseases (Alzheimer's disease, cardiovascular disease, cancer for example).