 | Study programme 2020-2021 | Français | |
| Nanotechnology - Controlled Release Systems | |||
Learning Activity |
| Code | Lecturer(s) | Associate Lecturer(s) | Subsitute Lecturer(s) et other(s) | Establishment |
|---|---|---|---|---|
| S-CHIM-077 |
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| Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term |
|---|---|---|---|---|---|---|---|
| Français | Français | 15 | 0 | 0 | 0 | 0 | Q2 |
| Organisational online arrangements for the end of Q3 2020-2021 assessments (Covid-19) |
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| Description of the modifications to the Q3 2020-2021 assessment procedures (Covid-19) |
| Not applicable |
Organisational arrangements for the end of Q2 2020-2021 assessments (Covid-19) online or face-to-face (according to assessment schedule)
- Oral exam (questions and answers, presentation of individual or group work, comment and argument about a written text...)
Description of the modifications to the Q2 2020-2021 assessment procedures (Covid-19) online or face-to-face (according to assessment schedule)
Not applicable
Content of Learning Activity
I.Introduction I.1. Terminology a. Controlled release b. Prolonged-Sustained release c. Drug targeting I.2. Objectives of controlled release drugs II.Factors Influencing the Design and Operation of Controlled / Extended-Release Drugs III. Physicochemical properties of the drug substances influencing the design and the efficacy of the dosage form a. Partition Coefficient b. Degree of ionization c. Molar mass and molecular volume d. Solubility e. Stability f. Protein binding IV.Biological properties of the drug substance influencing the design and efficacy of a controlled / prolonged release drug IV.1. Absorption IV.2. Distribution IV.3. Metabolisation IV.4. Elimination V.Controlled release forms a. Twox classes b. Polymers employed b.1. Glossary of polymer used b.1.1. Natural polymers b.1.2. Synthetic polymers A. Carbonated polymers B. Polymers with heteroatoms c. Microencapsulation c.1. Application of micro/nanoencapsulation c.2. Incorporation of drugs - Chemical conjugation (prodrug) - Physical entrapment - Polyionic complexation d. Nanovectorisation of drugs and tumor targeting d.1. Definition and illustrations d.2. First generation vectors d.3. Second generation vectors d.4. Third generation vectors d.5. Tumor targeting
Required Learning Resources/Tools
"Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists" Eds. Hillery, Lloyd and Swarbrick, 2001 Taylor & Francis
Recommended Learning Resources/Tools
Not applicable
Other Recommended Reading
Not applicable
Mode of delivery
- From a distance
Type of Teaching Activity/Activities
- Cours magistraux
Evaluations
The assessment methods of the Learning Activity (AA) are specified in the course description of the corresponding Educational Component (UE)