Neurotoxicology and Safety Pharmacology

		Study programme 2020-2021	Français
		Neurotoxicology and Safety Pharmacology
		Learning Activity

Code	Lecturer(s)	Associate Lecturer(s)	Subsitute Lecturer(s) et other(s)	Establishment
M-DOYM-129			COLOMAR Aurore	UMONS

Language of instruction	Language of assessment	HT(*)	HTPE(*)	HTPS(*)	HR(*)	HD(*)	Term
Anglais	Anglais	30	0	0	0	0	Q1

Organisational online arrangements for the end of Q3 2020-2021 assessments (Covid-19)
Oral exam (questions and answers, presentation of individual or group work, comment and argument about a written text...) Production of individual or group work, essay, report, dissertation...
Description of the modifications to the Q3 2020-2021 assessment procedures (Covid-19)
I will transmit an original article on neurotoxicology or safey pharmacology with questions to be answered by the student. Each student will have to send me back his/her answers. In a second step, I will discuss with each student about his/her work, to clarify some doubtful points and to check his/her involvement in his/her production. This will last 15 minutes. I will give only one quote integrating the evaluation of the writing part and of the discussion. For the planning, the article and questions will be sent 3 weeks before the oral examination. I will let 2 weeks to work on the article. I will have 1 week to read the written work. The oral dicussion will be planned during the exam session of August in face to face at the University. I will communicate the quote at the end of the entire oral session.

Organisational arrangements for the end of Q1 2020-2021 assessments (Covid-19) online or face-to-face (according to assessment schedule)

Oral exam (questions and answers, presentation of individual or group work, comment and argument about a written text...)
Production of individual or group work, essay, report, dissertation...

Description of the modifications to the Q1 2020-2021 online assessment procedures (Covid-19) online or face-to-face (according to assessment schedule)

I will transmit an original article on neurotoxicology or safey pharmacology with questions to be answered by the student. Each student will have to send me back his/her answers.
In a second step, I will discuss with each student about his/her work, to clarify some doubtful points and to check his/her involvement in his/her production. This will last 15 minutes. I will give only one quote integrating the evaluation of the writing part and of the discussion.
For the temporal agenda, the articles and questions will be sent after the memory redaction of mid-December. I will let at least 2 weeks to work on the article. The oral dicussion will be planned during the exam session of January, by Teams. I will communicate the quotes at the end of the entire oral session.

Content of Learning Activity

Reminder in Neurophysiology/Neuropharmacology: Structures, Functions of Nervous System (NS), neurotransmitters, barriers, metabolism, development. Pharmacology, Safety pharmacology, Toxicology notions: class effects, on-target & off target effects, dose, concentration, brain penetration, routes of administration...
Safety Pharmacology: Regulatory requirement for Nervous System, Acute & functional effects, Neurobehavioural assessment, Seizure liability, Drug abuse potential, Testing
Neurotoxicology (mature organisms): Regulatory requirement (drug, chemicals), Toxic Syndromes, Heavy metals, Gaz, Chemical compounds, Pesticids, Alcohol, Neurotoxins: animal, plants, mushrooms, bacteria.. Testing
Developmental Neurotoxicology: NS Development, critical periods, Regulatory requirement, Heavy metals, chemical compounds, pesticids, alcohol, tobacco, Testing
Endocrine disruptors: effects during NS development, effects on sex specific brain regions
Risk assessment: Hazard identification, on/off target effect, intrinsic toxicity, DMPK, exposure, risk evaluation and mitigation, population, acute and long-term effects

Required Learning Resources/Tools

Not applicable

Recommended Learning Resources/Tools

Not applicable